Education
PhD in Mathematics, University of Minnesota, 2003 - 2008 (focus: mathematical biology)
Visiting Graduate Student, Massachusetts Institute of Technology, 11/2005, 11/2006
BS in Computational Mathematics, Peking University, 1999 - 2003
Appointments
Founder & Director, Dr. Xue’s Math School, 2023 - now
Associate Professor, School of Mathematics, University of Minnesota, 2020 - 2021
Associate Director, Mathematical Biosciences Institute, Ohio State University, 2019 - 2020
Associate Professor, Department of Mathematics, Ohio State University, 2017 - 2020
Faculty Member, Biophysics Graduate Program, Ohio State University, 2015 - 2020
Visiting Faculty Member, University of Oxford, 02-03/2012
Assistant Professor, Department of Mathematics, Ohio State University, 2011 - 2017
NSF Postdoc Fellow, Mathematical Biosciences Institute, Ohio State University, 2008 - 2011
Selected Awards
Presidential Early Career Award for Scientists and Engineers (PECASE), issued by the White House, 2017
NSF Career Award, issued by the National Science Foundation, 2016
MBI Cosponsored Postdoc Fellow Award, issued by Mathematical Biosciences Institute, OSU, 2009
Jiang Zehan Scholarship for excellent student, issued by Peking University, 2002
Selected Research Grants
NSF-DMS 1553637. CAREER: Multiscale modeling of axonal cytoskeleton dynamics and axonal transport, 06/2016-05/2021. Role: sole PI.
NSF-MCB. Function and mechanism of action of plant-specific LINC complexes in pollen tube and guard cell biology, 07/2016-06/2019. Role: senior personnel.
NSF-DMS 1312966. Multiscale Models of Bacterial Chemotaxis and Phase Segregation in Axons, 09/2013 - 08/2017. Role: sole PI.
Selected Publications
B. W. Scandling, J. Gou, J. Thomas, J. Xuan, C. Xue, and K. J. Gooch. A Motor clutch model predicts and suggests mechanisms of cellular morphological response to cyclic force. Molecular Biology of the Cell. Molecular Biology of the Cell, 2022. (co-corresponding author)
T. Hillen, K. Painter, M. Stolarska and C. Xue. Multiscale phenomena and patterns in biological systems: Special Issue in honor of the 75th birthday of Hans Othmer. J. Math. Biol., 2020.
W. Hao and C. Xue. Spatial pattern formation in reaction-diffusion models: a computational approach. J. Math. Biol., 2020.
X. Lai, A. Brown, and C. Xue. A stochastic model that explains axonal organelle pileups induced by a reduction of molecular motors. J Royal Soc. Interface, 2018.
C. Xue. Bacterial chemotaxis: a classic example of multiscale modeling in biology. Cell Movement: Modeling and Applications. Springer, 2018.
X. Xue, C. Xue and M. Tang. The role of intracellular signaling in the stripe formation in engineered E.coli populations. PLoS Comp. Biol., 2018. (co-corresponding author)
C. Xue and G. Jameson. Recent mathematical models of axonal transport. Stochastic Processes, Multiscale Modeling, and Numerical Methods for Computational Cellular Biology. Springer, Cham, 2017. 265-285.
C. Xue and X. Yang. Moment-flux models for bacterial chemotaxis in large signal gradients, J. Math. Biol., published online, 2016.
C. Xue, B. Shytulla, and A. Brown. A stochastic multiscale model that explains the segregation of axonal microtubules and neurofilaments in neurological diseases, PLoS Comp. Biol., 2015.
T. Li, A. Sues, M. Winkler, and C. Xue. Global small-data solutions of a two-dimensional chemotaxis system with rotational flux terms, Math. Mod. Meth. Appl. S, Vol 25, Issue 4, pp 721-746, M3AS, 2015.
C. Xue. Macroscopic equations for bacterial chemotaxis: integration of detailed biochemistry of cell signaling, J. Math. Biol., Volume 70, Issue 1-2, pp 1-44, 2015.
B. Franz, C. Xue, K. Painter, and R. Erban. Travelling waves in hybrid chemotaxis models, Bull. Math. biol., 76(2): 377-400, 2014.
A. Friedman, B. Hu and C. Xue. On a multiphase multicomponent model of biofilm growth, Arch. Ration. Mech. Anal., 211(1): 257-300, 2014.
Y. Louzoun, C. Xue, G. Lesinski, and A. Friedman. A mathematical model for pancreatic cancer growth and treatments, J. Theor. Biol., 351(21): 74-82, 2014.
H. Othmer, X. Xin, and C. Xue. Excitation and adaptation in bacteria -- a model signal transduction system that controls taxis and spatial pattern formation, International Journal of Molecular Sciences, 14(5), 9205-9248, 2013.
H. G. Othmer and C. Xue. The mathematical analysis of biological aggregation and dispersal: progress, problems and perspectives, Dispersal, individual movement and spatial ecology: A mathematical perspective (edited by M. Lewis, P. Maini and S. Petrovskii), 2013.
A. Friedman, B. Hu, and C. Xue. A three dimensional model of chronic wound healing: analysis and computation, Discrete and Continuous Dynamical Systems - Series B, Vol. 17, No. 8, 2012.
C. Xue, E. O. Budrene-Kac, and H. G. Othmer. Radial and spiral stream formation in Proteus mirabilis colonies, PLoS Comput Biol 7(12): e1002332, 2011.
C. Xue, K. Painter, H. J. Hwang, and R. Erban. Traveling waves in hyperbolic chemotaxis equations, Bull. Math. Biol., 73(8):1695-733, 2011.
A. Friedman and C. Xue. A mathematical model of chronic wounds, Mathematical Biosciences and Engineering, 8(2):253-61, 2011.
A. Friedman, B. Hu, and C. Xue. Analysis of a mathematical model of ischemic wounds, SIAM Journal on Mathematical Analysis, Vol. 42, Issue 5, pp. 2013-2040, 2010.
C. Xue, H. G. Othmer, and R. Erban. From Individual to Collective Behavior of Unicellular Organisms: Recent Results and Open Problems, Multiscale Phenomena in Biology: Proceedings of the 2nd Okinawa Conference on Mathematics and Biology, AIP, Vol. 1167, pp. 3-14, 2009.
C. Xue, A. Friedman, and C. K. Sen. A mathematical model of ischemic cutaneous wounds, Proceedings of the National Academy of Sciences, Vol. 106, No. 39, pp. 16782-16787, 2009. PNAS cover highlight
H. G. Othmer, K. Painter, D. Umulis, and C. Xue. The Intersection of theory and application in elucidating pattern formation in developmental biology, Mathematical Modelling of Natural Phenomena, Vol. 4, No. 4, pp. 3-82, 2009.
C. Xue and H. G. Othmer. Multiscale models of taxis-driven patterning in bacterial populations, SIAM J. Appl. Math. Vol. 70, No. 1, pp. 133-167, 2009.
Other Experience in K-12 Education
Research Project Mentor, Summer Institute (high schoolers), Young Women’s Summer Institute (middle schoolers), Ohio Supercomputer Center, 2018 - 2020
Girl Scout Troop Co-Leader, 2018 - 2020